Tuesday, February 28, 2017

Cholesterol, and its effect on how the brain works

It seems that cholesterol affects more than the heart. It also seems to affect the adenosine receptors in the brain. Understanding how this works may have major ramifications for treating diseases like Alzheimer's and others like it.

"A study demonstrates that the cholesterol present in cell membranes can interfere with the function of an important brain membrane protein, through a previously unknown mode of interaction. Specifically, cholesterol is capable of regulating the activity of the adenosine receptor, by invading it and accessing the active site. This will allow new ways of interacting with these proteins to be devised that in the future could lead to drugs for treating diseases like Alzheimer's."